Integrated propranolol, methylprednisolone, and surgery in managing a rare case of infantile hemangioma with concurrent cleft lip and palate

Infantile hemangioma (IH) with concurrent cleft lip and palate is a rare case. Surgical management is often
considered as the best management for infantile hemangioma with concurrent cleft lip and palate. However,
considering the functionality aspect and aesthetic appearance, a plastic surgeon can also consider non-surgical
management without interrupting the surgical timeline for the cleft lip and palate. This case report aimed to
describe the role of oral propranolol and oral methylprednisolone for infantile hemangioma with concurrent
cleft lip and palate alongside the surgical management for cleft lip and palate.
A 2-month-old presented with complaints of swelling in her right upper nose and cheek along with cleft lip
and palate. She was treated with oral propranolol and oral methylprednisolone. Labioplasty was performed
when she was three months old. Palatoplasty and nasorraphy were done when she was one year old. A significant
reduction of the hemangioma was seen and the corrective procedures showed a good result.
The use of propranolol and methylprednisolone for infantile hemangioma in our patient shows a good result
even when combined with labioplasty, palatoplasty, and nasorraphy for cleft lip and palate.
The management of infantile hemangioma with concurrent cleft lip and palate using oral propranolol and oral
methylprednisolone shows a good result with no side effects and can be elaborated with labioplasty, palatoplasty,
and nasorraphy, and will not interrupt the cleft lip and palate surgical timeline.