Analysis of beta-crosslaps (Â-Ctx) and mandible trabecular parameters in menopausal women using cone beam computed tomography (Cbct)

The purpose of this study was to analyze the correlation between Beta-CrossLaps (β-CTx) and trabecular structural parameters of menopausal women using CBCT A total of 17 mandibular CBCT radiographs of menopausal women with laboratory tested of β- CTx were taken. Trabecular region of interest (ROI) sized 3 x 3 mm was choosen inferiorly from both side of mentale foramen make it a total of 34 ROI. Bone volume fraction (BV/TV), trabecular thickness (Tb.Th) and trabecular separation (Tb.Sp) was calculated using BoneJ on each ROI. Statistical analysis was done using SPSS. Pearson correlation to obtain the relationship of β-CTx with each parameter. There is no significant correlation (p> 0.05) between β-CTx with BV/TV (r= -0.252) and Tb.Th (r= 0.227). Meanwhile β-CTx has a significant positive correlation (p< 0.05) associated with Tb.Sp (r= 0.452). Increasing β-CTx level is not always followed by a decrease in BV/TV percentage and Tb.Th width. Tb.Sp is the most correlated parameter related to β-CTx. © 2019 University of Dicle.