Leukemia Cutis in An Adult Patient with Acute Lymphoblastic Leukemia: A Review of Histopathology and Immunohistochemistry in Diagnosis

Leukemia Cutis (LC) is a condition of cutaneous infiltration by neoplastic leukocytes. It can manifest in any leukemia, but LC caused by acute lymphoblastic leukemia (ALL) has the rarest incidence compared to other types of leukemia. The examination of histopathological morphology supported by immunohistochemical examination and its correlation with peripheral blood morphology and bone marrow is important in the final diagnosis of LC. We present a LC case of a 35-year-old male patient with ALL, using histopathological and immunohistochemistry examinations to diagnose. This case report aims to help clinicians establish the diagnosis for cutaneous manifestations in patients with ALL by using histopathological and immunohistochemical examinations. © 2024 THE AUTHORS.