Nano-Arsenal from the rainforest: Self-nanoemulsifying RFO (red fruit oil) for potent antimicrobial activity

Ollong, Abdul Rahman and Baskara, Aji Praba and Ariyadi, Bambang and Martien, Ronny and Arizona, Rizki and Zuprizal, Zuprizal (2025) Nano-Arsenal from the rainforest: Self-nanoemulsifying RFO (red fruit oil) for potent antimicrobial activity. In: BIO Web Conf., 24 October 2025, UNS Tower, Universitas Sebelas Maret (UNS) Surakarta, Jawa Tengah.

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Abstract

This study aimed to evaluate the antibacterial potential of a self-nanoemulsifying drug delivery system (SNEDDS) containing red fruit oil (RFO). Antimicrobial assays against Escherichia coli, Salmonella typhimurium, and Lactobacillus acidophilus included inhibition zone, minimum inhibitory concentration (MIC), and optical density (OD625) tests. Data were analyzed using one-way ANOVA and the Honestly Significant Difference (HSD) test. The results showed that RFO-SNEDDS selectively inhibited Gram-negative bacteria. The strongest effect was observed against Salmonella typhimurium, while sparing Lactobacillus acidophilus. These evidences emphasize the potential of RFO-SNEDDS as a natural antimicrobial with selective action. © 2025 The Authors.

Item Type: Conference or Workshop Item (Paper)
Additional Information: Conference name: 3rd International Conference on Animal Research for Eco-Friendly Livestock Industry, ICARELI 2025; Conference date: 14 October 2025 through 14 October 2025; Conference code: 216203; All Open Access, Gold Open Access, Green Open Access
Uncontrolled Keywords: Nano-Arsenal; the rainforest; Self-nanoemulsifying RFO (red fruit oil); potent antimicrobial activity
Subjects: S Agriculture > SF Animal culture
Divisions: Faculty of Animal Sciences > Department of Animal Nutrition and Feed Science
Depositing User: Uminurida SUCIATI
Date Deposited: 23 Jun 2026 00:34
Last Modified: 23 Jun 2026 00:34
URI: https://ir.lib.ugm.ac.id/id/eprint/27360

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