Chronic Submandibular Lymphadenopathy due to Cryptococcosis in Cat

Cryptococcosis is one of the systemic mycosis in cats. Although it was considered a potential zoonotic dis-ease, the transmission from cats to humans remains uncertain. This report observes the clinical and histopathological features of cryptococcosis in a cat exhibiting chronic submandibular lymphadenopathy. A five-year-old female cat showed lethargy, partial anorexia, weight loss, and intermittent sneezing for several months before being examined. Clinical examination demonstrated mucopurulent discharge from both nostrils, swollen on the nasal bridge and max-illary sinus. Subsequently, the cat was diagnosed infected by cryptococcosis based on cytology, fungal culture, serology, and hematology. Lymphadenopathy and the spreading of infection to the lungs were identified based on histopathological examination. Owing to potential zoonotic, a high index of suspicion was needed to identify mimickers like Cryptococcus spp. which in this case had initially presented as bilateral submandibular lymphadenopathy. The proper diagnosis and early treatment were needed to increase the chances of successful therapy. © 2023 by the authors. Licensee ResearchersLinks Ltd, England, UK.