The Electromagnetic Radiation Effect of Mobile Phone to the Inflammation Cells in Gingival (Rattus Norvegicus)

Introduction: Gingiva is one of the periodontal tissue that protects the tooth. Mobile phone’s electromagnetic radiation triggers Reactive Oxygen Species (ROS) production in the body hence causing gingival inflammation. Inflammatory mediators will initiate the migration of neutrophils, macrophages, mast cells, and lymphocytes. The purpose of this study was to investigate the effect of mobile phone electromagnetic radiation on neutrophil, macrophage, mast cell, and lymphocyte count in the gingival tissue of Rattus norvegicus. Methods: Fifteen rats were divided into three groups randomly. Group A was given electromagnetic radiation (2500-2700 MHz) exposure 24 hours per day for 14 days, Group B six hours per day for 14 days and group C was control group. Radiation was given at 12 cm distance from cages of group A and B. On the 14th day, labial gingiva of rat’s mandible was cut. Histological preparations were stained using Hematoxylin Eosin and measured the number of neutrophil, mast cell, macrophage, and lymphocyte. The data were analyzed by Kruskal Wallis and U-Mann Whitney. Results: There was significant difference between three groups of lymphocyte but no significant differences for neutrophil, mast cell, and macrophage. Conclusion: The conclusion is 2500-2700 MHz electromagnetic radiation of mobile phone for 14 days increase the number of lymphocyte on rat’s gingiva, but doesn’t increase the number of neutrophil, macrophage, and mast cell. © 2023 UPM Press. All rights reserved.