Computational assessment dose distribution of the antero-posterior and postero-anterior in Boron Neutron Capture Therapy for colorectal cancer

Colorectal is part of the gastrointestinal system that anatomically and physiologically, is excretory and extends throughout the abdominal region. In BNCT (Boron Neutron Capture Therapy) treatment for colorectal cancer, special projections are needed to ensure the dose is distributed effectively in cancer cells. Computational evaluation was carried out using PHITS 3.30 version, to determine the number of doses for organs at risk in the Antero-Posterior (AP) projection compared to the Postero-Anterior (PA) projection in this case, if the cancer cells are located in different parts, there are rectum and colon (transverse). BNCT treatment planning was designed using a female abdomen phantom voxel with the patient position Left Lateral Decubitus. Based on the simulation and evaluation results, it's confirmed that isoeffective dose and irradiation time examined in the rectum is significantly reduced in the postero-anterior position so that postero-anterior and antero-posterior calculation results are 0.74 Gy and 20.61 Gy. However, if the cancer cells are in the transverse colon, antero-posterior projection is more effective for cases of colon cancer in the transverse colon of 0.71 Gy, and the postero-anterior projection with a dose of 29.15 Gy. © Published under licence by IOP Publishing Ltd.