Associations between pesticide exposure with biomarkers of stroke risk factors in farmers

Setyopranoto, Ismail and Panggabean, Andre Stefanus and Dwianingsih, Ery Kus and Setyaningrum, Cempaka Thursina Srie and Sutarni, Sri and Malueka, Rusdy Ghazali and Rochmah, Mawaddah Ar (2024) Associations between pesticide exposure with biomarkers of stroke risk factors in farmers. Journal of Neurosciences in Rural Practice, 15 (1). 130 -133. ISSN 09763147

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Abstract

The extensive use of pesticides may cause acute and chronic intoxication. Therefore, this study aimed to reveal the associations between pesticide exposure and serum markers for stroke risk factors in farmers. A cross-sectional study was conducted with farmers, who used chemical pesticides in Seloprojo Village, Ngablak District, Magelang Regency, Central Java Province, Indonesia. A questionnaire containing demographics, pesticide use, and aspects related to work was employed. Measurements of serum cholesterol, uric acid, glucose, cholinesterase, and fibrinogen levels were also conducted. Of the 106 subjects, 31 (29.2) used organophosphates as chemical pesticides. There was a significant difference between organophosphate and non-organophosphate groups in plasma fibrinogen levels. The organophosphate group had higher levels of fibrinogen (292.29 ± 67.56 mg/dL) than the non-organophosphate group (255.24 ± 38.90 mg/dL). Of the studied risk factors for stroke, there is a significant association between organophosphate exposure and increased plasma fibrinogen levels. © 2024 Published by Scientific Scholar on behalf of Journal of Neurosciences in Rural Practice.

Item Type: Article
Additional Information: Cited by: 2; All Open Access, Gold Open Access, Green Open Access
Uncontrolled Keywords: cholesterol; cholinesterase; fibrinogen; glucose; non organophosphate pesticide; organophosphate pesticide; pesticide; unclassified drug; uric acid; adult; agricultural worker; Article; body mass; cerebrovascular accident; cholesterol blood level; cholinesterase blood level; controlled study; cross-sectional study; demographics; diastolic blood pressure; educational status; female; fibrinogen blood level; glucose blood level; human; Indonesia; major clinical study; male; middle aged; occupational exposure; questionnaire; risk factor; smoking; systolic blood pressure; uric acid blood level
Subjects: R Medicine > RN Non Surgical Divisions
Divisions: Faculty of Medicine, Public Health and Nursing > Non Surgical Divisions
Depositing User: Mukhotib Mukhotib
Date Deposited: 14 Mar 2025 01:46
Last Modified: 14 Mar 2025 01:46
URI: https://ir.lib.ugm.ac.id/id/eprint/15746

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