Rinonce, Hanggoro Tri and Aji, Rovi Panji Mustiko and Hayati, Ni'mah and Pudjohartono, Maria Fransiska and Kameswari, Bidari and Anwar, Sumadi Lukman and Irianiwati, Irianiwati (2020) BRAF V600 mutation profiling in primary skin nodular melanoma in Indonesia: an analysis using high resolution pyrosequencing. BMC Research Notes, 13 (1). ISSN 17560500
Full text not available from this repository. (Request a copy)Abstract
Objective. We aimed to investigate the prevalence and type of BRAF V600 mutations and the associations with clinicopathological variables in primary skin nodular melanoma cases in Yogyakarta and Central Java, Indonesia using pyrosequencing.
Results. BRAF V600 mutations of the V600E type were found in 21 (53.85%) specimens. The variant allele frequencies (VAFs) ranged from 5.07 to 94.70%, averaging 29.05%. However, most cases had low VAFs, with 13 (61.9%) specimens below 20% and 4 (19.05%) below 10%.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Melanoma, Skin cancer, BRAF, Pyrosequencing, Indonesia |
| Subjects: | R Medicine > RZ Other systems of medicine |
| Divisions: | Faculty of Medicine, Public Health and Nursing > Public Health and Nutrition |
| Depositing User: | Sri JUNANDI |
| Date Deposited: | 05 Jun 2025 08:41 |
| Last Modified: | 05 Jun 2025 08:41 |
| URI: | https://ir.lib.ugm.ac.id/id/eprint/17447 |
Actions (login required)
- View Item