Potential of indonesian bay leaf (Syzygium polyanthum) as anthelmintics against ascaridia galli

Anthelmintic resistance has emerged as a major problem in parasite control, hence, it is necessary to explore the possibility of using herbal plants as an alternative to anthelmintics. This study aims to determine the potential of ethanolic extract of Indonesian bay leaves as an anthelmintic alternative against Ascaridia galli. Phytochemical method was performed for testing the chemical compounds present in the extract. In vitro study was conducted to determine the effect of Indonesian bay leaf extract (BLE) on the resistance of worm movement, which was then evaluated ultra-structurally using Scanning Electron Microscope. This study was conducted with 4 experimental groups, consisting of 3 BLE treatment groups with varying degrees of solution concentrations (2, 8, 14) and a negative control group. Mortality data were analyzed for its variances with ANOVA. Means among treatments were compared by Duncan Multiple Range Test (DMRT). Statistical differences were expressed at P<0.05.The results showed that A. galli in all groups did not die during the 10 hours immersion. BLE up to a concentration of 14 can damage the cuticle of A. galli. Based on this experiment, it was concluded that BLE is potential to be an anthelmintic against A. galli. Further research is needed to be conducted to determine the ideal dosage. © 2021 Elsevier B.V., All rights reserved.