Xanthan Gum and Propylene Glycol Effects on Physicochemical and Antioxidant Activities of Honey-based Syrup

Ardiningsih, Aulia Rahma and Hardyawati, Wimala and Isningroom, Mias and Darsih, Cici and Praharasti, Anggita Sari and Sahid, Muhammad Novrizal Abdi and Laksitorini, Marlyn Dian (2025) Xanthan Gum and Propylene Glycol Effects on Physicochemical and Antioxidant Activities of Honey-based Syrup. Natural and Life Sciences Communications, 24 (3).

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Abstract

Antioxidant supplements from natural ingredients can be an alternative to counteract the effects of free radicals. None of the products use a combination of Chrysanthemum indicum and Centella asiatica extracts formulated as antioxidant supplements, particularly in syrup form. To date, sugar has been commonly used as a syrup base. However, honey can also be used as a base for syrups as a sugar substitute, but it has antioxidant activity. This study evaluated the antioxidant activity of honey-based herbal syrup with varying concentrations of Xanthan Gum and Propylene Glycol. This study aims is to asses two Indonesian honeys' antioxidant capacity against Manuka honey as standard. Ceiba honey was selected as the base for herbal syrup due to its superior antioxidant activity. Subsequently, the antioxidant activity of the three active compounds used in the formula was assessed using DPPH, yielding a result of 272.82 ± 5.167 µg/ml, which falls into the weak category. The antioxidant activity of the honey-based syrup remained unaffected by the addition of propylene glycol and xanthan gum. The honey-based syrup was also subjected to a physical analysis, where pourability, density, and viscosity decreased as the composition of xanthan gum decreased compared to propylene glycol. Meanwhile, higher xanthan gum content increased water activity and a darker appearance. The simplex lattice design (SLD) method identified an optimal formulation containing 0.099 xanthan gum and 10.401 propylene glycol. Freeze-thaw stability testing confirmed the honey-based syrup maintained stable physical properties.

Item Type: Article
Additional Information: Cited by: 0
Uncontrolled Keywords: Antioxidant supplements; Honey-based syrup; Propylene glycol\; Xanthan gum; Stability test
Subjects: R Medicine > RM Therapeutics. Pharmacology
R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Pharmacy
Depositing User: Muh Aly Mubarok
Date Deposited: 27 Apr 2026 05:29
Last Modified: 27 Apr 2026 05:29
URI: https://ir.lib.ugm.ac.id/id/eprint/24282

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