Outcomes and survival of infants with congenital duodenal obstruction following Kimura procedure with post-anastomosis jejunostomy feeding tube

Makkadafi, Munawir and Fauzi, Aditya Rifqi and Wandita, Setya and Makhmudi, Akhmad and Gunadi, Gunadi (2021) Outcomes and survival of infants with congenital duodenal obstruction following Kimura procedure with post-anastomosis jejunostomy feeding tube. BMC Gastroenterology, 21 (1). ISSN 1471230X

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Abstract

Background: Several modifications of the Kimura procedure for congenital duodenal obstruction (CDO) have been reported, however, their effects on the outcomes show conflicting results. Methods: We compared the CDO outcomes following the Kimura procedure with and without post-anastomosis jejunostomy feeding tube (JFT). Results: A total of 52 CDO neonates were involved (JFT: 13 males and 2 females vs. non-JFT: 14 males and 23 females, p = 0.0019). Time to full oral feeding was significantly earlier in the JFT than non-JFT group (14 interquartile range (IQR), 12–15 vs. 17 IQR, 14–22.5 days; p = 0.04). Duration of parenteral nutrition given to infants with CDO after surgery was significantly shorter in the JFT than non-JFT group (12 IQR, 10–15 vs. 17 IQR, 13–23 days; p = 0.031). Moreover, enteral feeding was significantly earlier in the JFT than non-JFT group (2 IQR, 1–3.5 vs. 5 IQR, 4–6 days; p = < 0.0001). However, the length of stay following surgery was not significantly different between groups (16 IQR, 14–22 vs. 20 IQR, 17–28 days; p = 0.22). Also, overall patient survival did not significantly differ between JFT (66.7%) and non-JFT patients (59.5%) (p = 0.61). Conclusion: Jejunostomy feeding tube shows a beneficial effect on the time to full oral feeding, duration of parenteral nutrition and early enteral feeding in neonates with congenital duodenal obstruction after Kimura procedure. © 2021, The Author(s).

Item Type: Article
Additional Information: Cited by: 4; All Open Access, Gold Open Access, Green Open Access
Uncontrolled Keywords: Anastomosis, Surgical; Duodenal Obstruction; Enteral Nutrition; Female; Humans; Infant; Infant, Newborn; Jejunostomy; Male; Parenteral Nutrition; Retrospective Studies; age distribution; Article; clinical feature; comparative effectiveness; congenital duodenum obstruction; controlled study; duodenum obstruction; enteric feeding; female; human; Indonesia; infant; intestine anastomosis; intestine surgery; Kimura procedure; length of stay; major clinical study; male; outcome assessment; parenteral nutrition; pediatric patient; retrospective study; sex difference; survival rate; treatment outcome; treatment response; adverse event; anastomosis; duodenum obstruction; jejunostomy; newborn
Subjects: R Medicine > RD Surgical Divisions
Divisions: Faculty of Medicine, Public Health and Nursing > Biomedical Sciences
Depositing User: Sri JUNANDI
Date Deposited: 28 Sep 2024 02:50
Last Modified: 28 Sep 2024 02:50
URI: https://ir.lib.ugm.ac.id/id/eprint/4492

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