Quality of life of drug reaction with eosinophilia and systemic symptom (Dress) and stevens-johnson syndrome (sjs) and/or toxic epidermal necrolysis (ten) patients

Perwitasari, Dyah Aryani and Febriana, Sri Awalia and Tristiana, Ratna Septi (2021) Quality of life of drug reaction with eosinophilia and systemic symptom (Dress) and stevens-johnson syndrome (sjs) and/or toxic epidermal necrolysis (ten) patients. Patient Preference and Adherence, 15. pp. 329-335. ISSN 1177889X

[thumbnail of Sri Awalia_KKMK.pdf] Text
Sri Awalia_KKMK.pdf - Published Version
Restricted to Registered users only

Download (287kB) | Request a copy

Abstract

Purpose: Drug Reaction With Eosinophilia and Systemic Symptom (DRESS), Stevens-Johnson Syndrome (SJS), and Toxic Epidermal Necrolysis (TEN) are acute hypersensitivity reactions with the potential to reduce the quality of life of exposed individuals. This study aims to determine the quality of life of patients suffering from DRESS, SJS, SJS/TEN. Patients and Methods: A cross-sectional approach was used to get the quality of life data from DRESS, SJS, and/or TEN patients at Dr. Sardjito general hospital, Yogyakarta. The utility index and VAS score differences of EQ-5D-5L were analyzed based on the diagnosis. Results: We recruited 58 patients. Most of the patients were female (63). The mean value of utility index was 0.61, 0.08 and 0.03 for DRESS, SJS and SJS/TEN patients, respectively (p value <0.01). Furthermore, the mean of VAS score was 73.36, 57.93 and 50.00 for DRESS, SJS and SJS/TEN patients, respectively (p value <0.01). Conclusion: In general, the quality of life of DRESS patients is better than the quality of life of SJS and/or TEN patients. © 2021 Perwitasari et al.

Item Type: Article
Additional Information: Cited by: 6; All Open Access, Gold Open Access, Green Open Access
Uncontrolled Keywords: antibiotic agent; anticonvulsive agent; corticosteroid; cyclosporine; nonsteroid antiinflammatory agent; tuberculostatic agent; adult; Article; controlled study; cross-sectional study; demography; disease association; DRESS syndrome; eosinophilia; European Quality of Life 5 Dimensions 5 Level questionnaire; female; fluid therapy; hospitalization; human; ICD-10; Indonesia; major clinical study; male; observational study; prospective study; Stevens Johnson syndrome; toxic epidermal necrolysis; visual analog scale
Subjects: R Medicine > RL Dermatology
Divisions: Faculty of Medicine, Public Health and Nursing > Biomedical Sciences
Depositing User: Sri JUNANDI
Date Deposited: 29 Aug 2024 08:42
Last Modified: 29 Aug 2024 08:42
URI: https://ir.lib.ugm.ac.id/id/eprint/4918

Actions (login required)

View Item
View Item