The Effect of Hibiscus Flower Extract (Hibiscus rosa-sinensis L.) on the Growth of Streptococcus sanguinis Bacteria

Farasayu, Ranty Dwi and Rachmawati, Mayu Winnie and Ana, Ika Dewi and Syaify, Ahmad and Listyarifah, Dyah (2021) The Effect of Hibiscus Flower Extract (Hibiscus rosa-sinensis L.) on the Growth of Streptococcus sanguinis Bacteria. In: The 4th International Conference on Bioinformatics, Biotechnology, and Biomedical Engineering (BioMIC 2021).

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Abstract

According to the data of Global Burden Disease in 2016, periodontal disease is the 11th disease suffered by 750,487 people worldwide. Gingivitis occurs due to dental plaque formation. A half of bacterial plaque populations are Streptococcus sp. Streptococcus sanguinis is a predominant bacterial that initiates plaque formation. The adherence of this bacteria is mediated by fimbriae, pilus protein, lipoprotein, and glucosyltransferase enzymes. Hibiscus flower has a potential as an antimicrobial agent that may inhibit plaque formation due its active component i.e. flavonoid, tannins, and saponin. This study aimed to investigate the effect of Hibiscus rosa-sinensis L. flower extract concentration on the growth of Streptococcus sanguinis. Wells diffusion method was used in this study, using 100 μl bacterial suspension of 1,5 × 108 CFU/ml of bacteria. Hibiscus flower extract (2, 4, 6), chlorhexidine 0,12 as a positive control, and distilled water as a negative control were added in the agar wells. The results showed that all concentrations (2 , 4, 6 ) of Hibiscus flower extract higher significantly compared to negative control. The concentration of 4 and 6 are higher;significantly compared to positive control. The largest inhibitory zone was at a concentration of 6 (6,35±0,09 mm) and the smallest inhibitory zone was at a concentration of 2 (2,51±0,12 mm). The conclusion is that the concentration of Hibiscus rosa-sinensis L. flower extract affects the growth of Streptococcus sanguinis. © The Authors, published by EDP Sciences. This is an open access article distributed under the terms of the Creative Commons Attribution License 4.0 (http://creativecommons.org/licenses/by/4.0/).

Item Type: Conference or Workshop Item (Paper)
Additional Information: Cited by: 1; Conference name: 4th International Conference on Bioinformatics, Biotechnology, and Biomedical Engineering, BioMIC 2021; Conference date: 6 October 2021 through 7 October 2021; Conference code: 192780; All Open Access, Gold Open Access
Uncontrolled Keywords: Kembang Sepatu Flower (Hibiscus rosa-sinensis L.), Hibiscus flower extract, Streptococcus sanguinis, zone of hibition, antibacterial
Subjects: R Medicine > RK Dentistry
Divisions: Faculty of Dentistry > Dental Hygiene Study Program
Depositing User: Sri JUNANDI
Date Deposited: 10 Sep 2024 06:45
Last Modified: 10 Sep 2024 06:45
URI: https://ir.lib.ugm.ac.id/id/eprint/5566

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