Farasayu, Ranty Dwi and Rachmawati, Mayu Winnie and Ana, Ika Dewi and Syaify, Ahmad and Listyarifah, Dyah (2021) The Effect of Hibiscus Flower Extract (Hibiscus rosa-sinensis L.) on the Growth of Streptococcus sanguinis Bacteria. In: The 4th International Conference on Bioinformatics, Biotechnology, and Biomedical Engineering (BioMIC 2021).
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Abstract
According to the data of Global Burden Disease in 2016, periodontal disease is the 11th disease suffered by 750,487 people worldwide. Gingivitis occurs due to dental plaque formation. A half of bacterial plaque populations are Streptococcus sp. Streptococcus sanguinis is a predominant bacterial that initiates plaque formation. The adherence of this bacteria is mediated by fimbriae, pilus protein, lipoprotein, and glucosyltransferase enzymes. Hibiscus flower has a potential as an antimicrobial agent that may inhibit plaque formation due its active component i.e. flavonoid, tannins, and saponin. This study aimed to investigate the effect of Hibiscus rosa-sinensis L. flower extract concentration on the growth of Streptococcus sanguinis. Wells diffusion method was used in this study, using 100 μl bacterial suspension of 1,5 × 108 CFU/ml of bacteria. Hibiscus flower extract (2, 4, 6), chlorhexidine 0,12 as a positive control, and distilled water as a negative control were added in the agar wells. The results showed that all concentrations (2 , 4, 6 ) of Hibiscus flower extract higher significantly compared to negative control. The concentration of 4 and 6 are higher;significantly compared to positive control. The largest inhibitory zone was at a concentration of 6 (6,35±0,09 mm) and the smallest inhibitory zone was at a concentration of 2 (2,51±0,12 mm). The conclusion is that the concentration of Hibiscus rosa-sinensis L. flower extract affects the growth of Streptococcus sanguinis. © The Authors, published by EDP Sciences. This is an open access article distributed under the terms of the Creative Commons Attribution License 4.0 (http://creativecommons.org/licenses/by/4.0/).
Item Type: | Conference or Workshop Item (Paper) |
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Additional Information: | Cited by: 1; Conference name: 4th International Conference on Bioinformatics, Biotechnology, and Biomedical Engineering, BioMIC 2021; Conference date: 6 October 2021 through 7 October 2021; Conference code: 192780; All Open Access, Gold Open Access |
Uncontrolled Keywords: | Kembang Sepatu Flower (Hibiscus rosa-sinensis L.), Hibiscus flower extract, Streptococcus sanguinis, zone of hibition, antibacterial |
Subjects: | R Medicine > RK Dentistry |
Divisions: | Faculty of Dentistry > Dental Hygiene Study Program |
Depositing User: | Sri JUNANDI |
Date Deposited: | 10 Sep 2024 06:45 |
Last Modified: | 10 Sep 2024 06:45 |
URI: | https://ir.lib.ugm.ac.id/id/eprint/5566 |