Prastiyanto, Muhammad E. and Iswara, Arya and Khairunnisa, Afifah and Sofyantoro, Fajar and Siregar, Abdul R. and Mafiroh, Wulan U. and Setiawan, Jajar and Nadifah, Fitri and Wibowo, Anjar T. and Putri, Wahyu A. (2024) Prevalence and antimicrobial resistance profiles of multidrug-resistant bacterial isolates from urinary tract infections in Indonesian patients: A cross-sectional study. Clinical Infection in Practice, 22. ISSN 2590-1702
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Abstract
This study aimed to determine the prevalence of multidrug-resistant (MDR) bacterial isolates in urinary tract
infections (UTI) patients in Indonesia, where access to appropriate antibiotic treatment may be limited. A crosssectional study was conducted from January 2020 to December 2022, with 308 bacterial isolates from UTIs
cultured and tested for antimicrobial susceptibility. The most identified bacterial isolate was Escherichia coli
(39.6 %), followed by Klebsiella pneumoniae (11.6 %) and Staphylococcus spp. (11.03 %). The overall prevalence
of MDR bacterial isolates was 35 %, with the highest resistance observed to ampicillin (60 %) and cotrimoxazole
(50 %). Independent risk factors for the development of MDR UTIs included age (p = 0.03) and male sex (p =
0.02). These findings underscore the need for ongoing monitoring of antibiotic resistance patterns and the
development of antimicrobial stewardship programs to address this public health issue in Indonesia
Item Type: | Article |
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Additional Information: | Cited by: 1; All Open Access, Gold Open Access |
Uncontrolled Keywords: | Antibiotic Multi-drug resistance Urinary tract infections Indonesia Health risk |
Subjects: | Q Science > QH Natural history > QH301 Biology |
Divisions: | Faculty of Biology > Undergratuate Program in Biology |
Depositing User: | Ekowati Purwandari Purwandari |
Date Deposited: | 30 Sep 2024 02:53 |
Last Modified: | 30 Sep 2024 02:53 |
URI: | https://ir.lib.ugm.ac.id/id/eprint/6406 |