Prastiyanto, Muhammad E. and Iswara, Arya and Khairunnisa, Afifah and Sofyantoro, Fajar and Siregar, Abdul R. and Mafiroh, Wulan U. and Setiawan, Jajar and Nadifah, Fitri and Wibowo, Anjar T. and Putri, Wahyu A. (2024) Prevalence and antimicrobial resistance profiles of multidrug-resistant bacterial isolates from urinary tract infections in Indonesian patients: A cross-sectional study. Clinical Infection in Practice, 22. pp. 1-7. ISSN 25901702
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Abstract
This study aimed to determine the prevalence of multidrug-resistant (MDR) bacterial isolates in urinary tract infections (UTI) patients in Indonesia, where access to appropriate antibiotic treatment may be limited. A cross-sectional study was conducted from January 2020 to December 2022, with 308 bacterial isolates from UTIs cultured and tested for antimicrobial susceptibility. The most identified bacterial isolate was Escherichia coli (39.6 ), followed by Klebsiella pneumoniae (11.6 ) and Staphylococcus spp. (11.03 ). The overall prevalence of MDR bacterial isolates was 35 , with the highest resistance observed to ampicillin (60 ) and cotrimoxazole (50 ). Independent risk factors for the development of MDR UTIs included age (p = 0.03) and male sex (p = 0.02). These findings underscore the need for ongoing monitoring of antibiotic resistance patterns and the development of antimicrobial stewardship programs to address this public health issue in Indonesia. © 2024 The Author(s)
Item Type: | Article |
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Additional Information: | Cited by: 1; All Open Access, Gold Open Access |
Uncontrolled Keywords: | Antibiotic; Multi-drug resistance; Urinary tract infections Indonesia; Health risk |
Subjects: | Q Science > QH Natural history > QH301 Biology |
Divisions: | Faculty of Biology > Doctoral Program in Biology |
Depositing User: | Rusna Nur Aini Aini |
Date Deposited: | 03 Oct 2024 04:34 |
Last Modified: | 03 Oct 2024 04:34 |
URI: | https://ir.lib.ugm.ac.id/id/eprint/6547 |