Genetic diversity of cervid Trypanosoma theileri in Honshu sika deer (Cervus nippon) in Japan

Rosyadi, Imron and Setsuda, Aogu and Eliakunda, Mafie and Takano, Ai and Maeda, Ken and Ito, Atsuko Saito and Suzuki, Kazuo and Sato, Hiroshi (2021) Genetic diversity of cervid Trypanosoma theileri in Honshu sika deer (Cervus nippon) in Japan. Parasitology (148): 13. pp. 1636-1647. ISSN 00311820

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Abstract

The taxonomy of ruminant Trypanosoma theileri and its relatives (Kinetoplastida: Trypanosomatidae) is controversial, with recent phylogenetic studies segregating T. theileri in cattle and other ruminants worldwide into two major genetic lineages (the TthI and TthII clades) based on genetic markers. In the present study, T. theileri-like trypanosomes isolated from Honshu sika deer (Cervus nippon) in the western Japan (YMG isolate) were genetically characterized using a number of genetic markers. Sika deer trypanosomes of the YMG isolate were genetically different from the Trypanosoma sp. TSD1 isolate previously recorded
from Hokkaido sika deer in northern Japan, with the former trypanosome isolate being genetically closer to European cervid trypanosomes and the bovine T. theileri TthII lineage. In contrast, the latter isolate exhibited greater relatedness to North American cervid trypanosomes and the bovine T. theileri TthI lineage, although a clear genetic distinction between these was apparent. Furthermore, trypanosomes in Honshu sika deer from the central part
of Japan harboured additional genetic diversity and were closer to either TSD1 or YMG isolates, while distinct from known T. theileri-related genotypes. Importantly, cervids and wild ruminants worldwide might harbour divergent descendants of a T. theileri ancestor, which exhibit rigid host specificity to either bovines or cervid species.

Item Type: Article
Uncontrolled Keywords: Cervus nippon; genetic diversity; gGAPDH; Japan; Megatrypanum; phylogeny; rDNA; sika deer; taxonomy; Trypanosoma theileri
Subjects: S Agriculture > SF Animal culture
Divisions: Faculty of Veterinary Medicine
Depositing User: Erlita Cahyaningtyas Cahyaningtyas
Date Deposited: 19 Sep 2024 03:02
Last Modified: 19 Sep 2024 03:02
URI: https://ir.lib.ugm.ac.id/id/eprint/7322

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