Kusrini, Eny and Safira, Alya Irma and Usman, Anwar and Prasetyanto, Eko Adi and Nugrahaningtyas, Khoirina Dwi and Santosa, Sri Juari (2023) Nanocomposites of Terbium Sulfide Nanoparticles with a Chitosan Capping Agent for Antibacterial Applications. Journal of Composites Science, 7 (1): 39. ISSN 2504477X
109. Nanocomposites-of-Terbium-Sulfide-Nanoparticles-with-a-Chitosan-Capping-Agent-for-Antibacterial-ApplicationsJournal-of-Composites-Science.pdf - Published Version
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Abstract
This study aims to investigate the effect of alkaline pH on the bottom-up synthesis of nanocomposites (NCs) containing terbium sulfide nanoparticles (Tb2S3 NPs), where chitosan (CS) was employed as a capping agent, along with evaluation of the antibacterial activity of these NCs. The NCs were characterized using spectroscopy (FESEM-EDX, Raman, FTIR, XRD, XPS, and DLS), zeta-potential, and TGA. The results of FE-SEM, XPS, Raman, and FTIR characterization support the formation of CS-Tb2S3 NPs. A pH variation from 9 to 11 during composite formation was shown to affect the size and composition of NCs. The antibacterial activity of CS-Tb2S3 NCs was studied by coating onto commercial contact lenses, where the best loading efficiency of NCs was 48%. The NCs prepared at pH 10 (without contact lenses) had greater antibacterial activity against Staphylococcus aureus, with a zone of inhibition diameter of 7.15 mm. The coating of NCs onto commercial contact lenses was less effective for inhibition of Staphylococcus aureus, in contrast with the greater activity observed for tetracycline. CS-Tb2S3 NCs offer promising antimicrobial properties that can be further optimized by control of the surface loading and accessibility of Tb2S3 NPs through further study of the role of the chitosan capping agent, since steric effects due to CS are likely to attenuate antimicrobial activity via reduced electron transfer in such nanocomposite systems.
Item Type: | Article |
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Uncontrolled Keywords: | antibacterial; capping agent; chitosan; contact lens; Tb2S3 nanocomposite |
Subjects: | Q Science > QD Chemistry |
Divisions: | Faculty of Mathematics and Natural Sciences > Chemistry Department |
Depositing User: | Ismu WIDARTO |
Date Deposited: | 20 Sep 2024 08:41 |
Last Modified: | 20 Sep 2024 08:41 |
URI: | https://ir.lib.ugm.ac.id/id/eprint/7381 |