Global burden of peripheral artery disease and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

Kim, Min Seo and Hwang, Jimin and Yon, Dong Keon and Lee, Seung Won and Jung, Se Yong and Park, Seoyeon and Johnson, Catherine Owens and Stark, Benjamin A. and Razo, Christian and Abbasian, Mohammadreza and Abbastabar, Hedayat and Abhari, Amir Parsa and Aboyans, Victor and Adane, Denberu Eshetie Adane and Adebayo, Oladimeji M. and Alahdab, Fares and Almustanyir, Sami and Aly, Hany and Ameyaw, Edward Kwabena and Anderson, Jason A. and Andrei, Catalina Liliana and Aryan, Zahra and Aujayeb, Avinash and Bagherieh, Sara and Baltatu, Ovidiu Constantin and Banach, Maciej and Bayileyegn, Nebiyou Simegnew and Bearne, Lindsay M. and Behnoush, Amir Hossein and Bensenor, Isabela M. and Bhaskar, Sonu and Bhat, Ajay Nagesh and Bhat, Vivek and Bikbov, Boris and Bintoro, Bagas Suryo and Burkart, Katrin and Cámera, Luis Alberto and Catapano, Alberico L. and Chandrasekar, Eeshwar K. and Charan, Jaykaran and Chattu, Vijay Kumar and Chi, Gerald and Chukwu, Isaac Sunday and Chung, Sheng-Chia and Cirillo, Massimo and Coberly, Kaleb and Costa, Vera Marisa and Dadras, Omid and Dai, Xiaochen and Do, Thanh Chi and Doshi, Rajkumar and Ekholuenetale, Michael and Elgendy, Islam Y. and Elhadi, Muhammed and Fagbamigbe, Adeniyi Francis and Feizkhah, Alireza and Fekadu, Ginenus and Gill, Paramjit Singh and Goldust, Mohamad and Golechha, Mahaveer and Guan, Shi-Yang and Gupta, Vivek Kumar and Hadei, Mostafa and Hadi, Najah R. and Hammoud, Ahmad and Hankey, Graeme J. and Harlianto, Netanja I. and Hasaballah, Ahmed I. and Hassan, Shoaib and Hassen, Mohammed Bheser and Heidari, Golnaz and Hostiuc, Mihaela and Ilesanmi, Olayinka Stephen and Iwagami, Masao and Jokar, Mohammad and Jonas, Jost B. and Joshua, Charity Ehimwenma and Jozwiak, Jacek Jerzy and Kazemian, Sina and Keykhaei, Mohammad and Khalaji, Amirmohammad and Khan, Moien A.B. and Khateri, Sorour and Kibret, Biruk Getahun and Korzh, Oleksii and Koulmane Laxminarayana, Sindhura Lakshmi and Krishan, Kewal and Kumar, Akshay and Kumar, Manoj and Kuttikkattu, Ambily and Laksono, Tri and Larijani, Bagher and Le, Thao Thi Thu and Lim, Stephen S. and Liu, Xuefeng and Lorkowski, Stefan and Magdy Abd El Razek, Hassan and Malhotra, Kashish and Manla, Yosef and Maugeri, Andrea and Mentis, Alexios-Fotios A. and Mestrovic, Tomislav and Micheletti Gomide Nogueira de Sá, Ana Carolina and Mirica, Andreea and Mirrakhimov, Erkin M. and Misganaw, Awoke and Mishra, Manish and Mohammad, Yousef and Mokdad, Ali H. and Moni, Mohammad Ali and Montasir, Ahmed Al and Moradi, Yousef and Moraga, Paula and Morovatdar, Negar and Mousavi-Aghdas, Seyed Ali and Murray, Christopher J.L. and Naghavi, Mohsen and Nair, Tapas Sadasivan and Nassereldine, Hasan and Natto, Zuhair S. and Nguyen, Dang H. and Nguyen, Hien Quang and Nguyen, Van Thanh and Noubiap, Jean Jacques and Oancea, Bogdan and Oliveira, Gláucia Maria Moraes and Owolabi, Mayowa O. and Padron-Monedero, Alicia and Perico, Norberto and Petcu, Ionela-Roxana and Radfar, Amir and Rafferty, Quinn and Rahman, Mosiur and Rahman, Muhammad Aziz and Ram, Pradhum and Rashedi, Sina and Rashid, Ahmed Mustafa and Rawaf, Salman and Remuzzi, Giuseppe and Renzaho, Andre M.N. and Rezaee, Malihe and Roever, Leonardo and Saad, Aly M.A. and Saadatagah, Seyedmohammad and Sadeghi, Masoumeh and Sahebkar, Amirhossein and Saleh, Mohamed A. and Samy, Abdallah M. and Santric-Milicevic, Milena M. and Sepanlou, Sadaf G. and Seylani, Allen and Sharfaei, Sadaf and Shorofi, Seyed Afshin and Singh, Jasvinder A. and Singh, Paramdeep and Spartalis, Michael and Sundström, Johan and Tan, Ker-Kan and Teramoto, Masayuki and Tharwat, Samar and Tyrovolas, Stefanos and Valadan Tahbaz, Sahel and Van den Eynde, Jef and Vart, Priya and Wang, Cong and Wang, Fang and Westerman, Ronny and Xia, Juan and Xu, Suowen and Yada, Dereje Y. and Yamagishi, Kazumasa and Yonemoto, Naohiro and Zahir, Mazyar and Zangiabadian, Moein and Zarrintan, Armin and Zastrozhin, Mikhail Sergeevich and Zastrozhina, Anasthasia and Zoladl, Mohammad and Hay, Simon I. and Shin, Jae Il and Roth, Gregory A. (2023) Global burden of peripheral artery disease and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. The Lancet Global Health, 11 (10). e1553-e1565. ISSN 2214109X

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Abstract

Background: Peripheral artery disease is a growing public health problem. We aimed to estimate the global disease burden of peripheral artery disease, its risk factors, and temporospatial trends to inform policy and public measures. Methods: Data on peripheral artery disease were modelled using the Global Burden of Disease, Injuries, and Risk Factors Study (GBD) 2019 database. Prevalence, disability-adjusted life years (DALYs), and mortality estimates of peripheral artery disease were extracted from GBD 2019. Total DALYs and age-standardised DALY rate of peripheral artery disease attributed to modifiable risk factors were also assessed. Findings: In 2019, the number of people aged 40 years and older with peripheral artery disease was 113 million (95 uncertainty interval UI 99·2–128·4), with a global prevalence of 1·52% (95% UI 1·33–1·72), of which 42·6% was in countries with low to middle Socio-demographic Index (SDI). The global prevalence of peripheral artery disease was higher in older people, (14·91% 12·41–17·87 in those aged 80–84 years), and was generally higher in females than in males. Globally, the total number of DALYs attributable to modifiable risk factors in 2019 accounted for 69·4% (64·2–74·3) of total peripheral artery disease DALYs. The prevalence of peripheral artery disease was highest in countries with high SDI and lowest in countries with low SDI, whereas DALY and mortality rates showed U-shaped curves, with the highest burden in the high and low SDI quintiles. Interpretation: The total number of people with peripheral artery disease has increased globally from 1990 to 2019. Despite the lower prevalence of peripheral artery disease in males and low-income countries, these groups showed similar DALY rates to females and higher-income countries, highlighting disproportionate burden in these groups. Modifiable risk factors were responsible for around 70% of the global peripheral artery disease burden. Public measures could mitigate the burden of peripheral artery disease by modifying risk factors. Funding: Bill & Melinda Gates Foundation. © 2023 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license

Item Type: Article
Additional Information: Cited by: 10; All Open Access, Green Open Access
Uncontrolled Keywords: Adult; Aged; Databases, Factual; Female; Global Burden of Disease; Humans; Income; Male; Middle Aged; Peripheral Arterial Disease; Risk Factors; glucose; sodium; adult; aged; Article; disability-adjusted life year; epidemiological data; female; global prevalence; global disease burden; glucose blood level; high income country; human; hypertension; incidence; kidney failure; low income country; male; middle aged; middle income country; morbidity; mortality rate; peripheral arterial disease; prevalence; risk factor; smoking; sociodemographic index; sociodemographics; very elderly; years lived with disability; years of life lost; factual database; income; risk factor
Subjects: R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Divisions: Faculty of Medicine, Public Health and Nursing > Public Health
Depositing User: Annisa Fitria Nur Azizah Annisa Fitria Nur Azizah
Date Deposited: 16 May 2024 07:31
Last Modified: 16 May 2024 07:31
URI: https://ir.lib.ugm.ac.id/id/eprint/1231

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