Murraya koenigii L. Spreng.: An updated review of chemical composition, pharmacological effects, and toxicity studies

Murraya koenigii (L.) Spreng, commonly known as curry leaves or “Salam India, ” belongs to the genus Murraya and the Rutaceae family. This is a potential medicinal plant highly valued for its distinctive aroma and bioactive compounds. A comprehensive review was conducted through an online study on websites such as PubMed, Science Direct, Scopus, and Google Scholar. Subsequently, previous studies reported that the chemical content of M. koenigii includes alkaloids, phenylpropanoids, alkanes, and sesquiterpenes. This plant exhibits a wide range of pharmacological activities such as antiinflammatory and analgesic effects, antidiabetic properties, anticancer activity, antioxidant activity, wound healing, antipyretic effects, immunomodulation, hepatoprotective effects, antihelminthic properties, antimicrobial activity, antiulcer effects, antidiarrheal effects, antiobesity effects, neuroprotection, and antitrichomonal activity. In addition, the toxicological tests on the extract of M. koenigii did not show signs of mortality or morbidity. Therefore, this study aims to examine the phytochemical content, pharmacological activities, and toxicity of M. koenigii, serving as the basis for future studies in the field of phytomedicine. © 2024 Yuvianti Dwi Franyoto et al. This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/).