Formulation of a Lotion with Ethanol Extract of Curcuma manga Val. as a UV B Sunscreen and Activity Test by UV-Vis Spectrophotometry

Temu mango (Curcuma manga Val) is a rhizome plant native to Indonesia that contains curcuminoid and flavonoid antioxidant compounds. These compounds are believed to act as UV-light protectors, especially UV B. In this study, we performed a qualitative test of the compound content in temu mango followed by formulation and activity testing of water in oil (w/o) sunscreen lotion of temu mango in vitro. The optimization of the w/o lotion formulation was performed using Design Expert® (DE) software version 9.0.4.1 with the Simplex Lattice Design method. The DE software obtained 13 runs of the w/o lotion formula and continued testing the physical property to determine the optimum formula. The optimum formula of lotion w/o predicted by DE software was tested for physical stability for over 4 weeks; and the SPF test, percent pigmentation, and percent erythema were determined by UV-Vis spectrophotometry. The present results suggested that temu mango extract provided an SPF value at a concentration of 0.3 mg/mL with an SPF value of 16.62. The optimum formula of the lotion w/o were 7 glycerin, 7 cera alba, 5 cetyl alcohol with a value of stickiness of 0.70 ± 0.03 s, spreadability of 13.20 ± 0.83 cm2, and viscosity of 95.19 ± 3.06 dPa.s. Referring to the storage results, the optimum formula of w/o lotion from temu mango extract was stable during a month of storage. The w/o lotion in the optimum formula produced an SPF value of 15.06 ± 0.39, erythema of 10.95, and percent pigmentation of 10.41. © 2024 by Indonesian Journal of Pharmacy (IJP).