Principal component analysis of antioxidant activities, total phenolic contents, and total flavonoid contents of turmeric (Curcuma longa l.)

Rohman, Abdul F. and Theresia Can, Adelin and Irnawati, Irnawati and Rafi, Mohamad and Lukitaningsih, Endang and Fadzillah, Nurrulhidayah Ahmad (2020) Principal component analysis of antioxidant activities, total phenolic contents, and total flavonoid contents of turmeric (Curcuma longa l.). International Journal of Pharmaceutical Research, 12. 2966 - 2972. ISSN 09752366

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Abstract

Turmeric (Curcuma longa L.) is often used in the treatment of several diseases. Scientifically, turmeric has been shown to have antioxidant activity and the group of compounds that play a role in this regard is the curcuminoid, a compound belonging to the phenolic group. In addition, turmeric also contains secondary metabolites, such as flavonoids, which are also shown to have antioxidant activity. This study aims to determine the profile of total phenolic content, flavonoids, and antioxidant activity of turmeric extract from various markets in Central Java, East Java, and Special District of Yogyakarta and to perform Principal Component Analysis (PCA) for grouping the turmeric. Turmeric rhizome samples were prepared and macerated with methanol. The methanolic extracts were determined for its total phenolic content by the Folin-Ciocalteu method, flavonoids with AlCl<inf>3</inf> reagent, and antioxidant activity by DPPH method, and then subjected to chemometrics analysis using PCA dan Cluster Analysis (CA). The profiles of phenolic, flavonoid, and IC<inf>50</inf> values in each sample were different due to various factors that influence the content of secondary metabolites. The results also revealed that PCA method did not succeed in grouping turmeric samples because there was no correlation among variables, but CA method could provide the grouping of turmeric samples into six groups based on the variables used. © 2020 Elsevier B.V., All rights reserved.

Item Type: Article
Additional Information: Cited by: 2
Uncontrolled Keywords: antioxidant; Curcuma longa extract; flavonoid; gallic acid; phenol derivative; tannin; antioxidant activity; Article; chemometrics; controlled study; Curcuma longa; DPPH radical scavenging assay; IC50; melting point; moisture; nonhuman; phylogenetic tree; plant leaf; principal component analysis
Subjects: R Medicine > R Medicine (General)
R Medicine > RM Therapeutics. Pharmacology
R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Pharmacy
Depositing User: Sri JUNANDI
Date Deposited: 07 Oct 2025 02:04
Last Modified: 07 Oct 2025 02:04
URI: https://ir.lib.ugm.ac.id/id/eprint/21819

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