Vitamin D Levels in Pre-frail Older Adults and Its Correlation with Hand Grip Strength

Dwimartutie, Noto and Setiati, Siti and Tamin, Tirza Z. and Prijanti, Ani Retno and Harahap, Alida R. and Purnamasari, Dyah and Harimurti, Kuntjoro and Pramantara, I Dewa Putu (2023) Vitamin D Levels in Pre-frail Older Adults and Its Correlation with Hand Grip Strength. Acta Medica Indonesiana, 55 (2). pp. 172-179. ISSN 01259326

[thumbnail of 406_noto dwimartutie.pdf] Text
406_noto dwimartutie.pdf - Published Version
Restricted to Registered users only
Available under License Creative Commons Attribution.

Download (471kB) | Request a copy

Abstract

Background: Vitamin D deficiency is frequent in older adults and associated with poor musculoskeletal function. The prevalence of pre-frailty is also high in older persons, who may proceed to a frail state. This study aimed to determine the vitamin D levels in pre-frail older adults and its correlation with hand grip strength. Methods: A cross-sectional study was conducted on older adults (age > 60 years) with a pre-frail condition who were visiting the outpatient geriatric clinic at Cipto Mangunkusumo Hospital in Jakarta, Indonesia. Serum levels of vitamin D, measured as 25(OH)D, were determined by enzyme-linked immunosorbent assay (ELISA), and hand grip strength was measured using a Jamar hydraulic dynamometer. Correlations between vitamin D levels and hand grip strength were evaluated by Spearman’s rank correlation coefficient. Multiple linear regression analysis was carried out to assess contribution of variables that influence hand grip strength. Results: Of 95 pre-frail older adults (mean age 70.08 ± 5.35 years), 67.4 were female, and the median vitamin D level was 17.91 (interquartile range/IQR 13.68–26.36) ng/mL. Overall, 11.6 of the participants had normal vitamin D levels, whereas 34.7 and 53.7 had insufficient and deficient levels, respectively. Females were more likely to have inadequacy of vitamin D than males. Those with vitamin D deficiency tended to have a higher body mass index (BMI) and lower vitamin D intake than normal levels. A significant correlation between serum vitamin D levels and hand grip strength was observed (r = 0,283; P = 0,006). After adjusting for age, comorbidities, nutritional status, functional status, BMI, protein intake, and sun exposure score, regression analysis between hand grip strength and vitamin D levels gave standard coefficient beta = 0,255 (P = 0,013). Conclusion: In this study, pre-frail older adults had a high proportion of deficient and insufficient vitamin D levels, and a significant correlation was found between serum vitamin D levels and hand grip strength. © 2023, Indonesian Society of Internal Medicine. All rights reserved.

Item Type: Article
Additional Information: Library Dosen
Uncontrolled Keywords: Hand grip strength, older adults, pre-frail, vitamin D level
Subjects: R Medicine > R Medicine (General)
R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Divisions: Faculty of Medicine, Public Health and Nursing > Biomedical Sciences
Depositing User: Ngesti Gandini
Date Deposited: 19 Jun 2024 06:06
Last Modified: 19 Jun 2024 06:06
URI: https://ir.lib.ugm.ac.id/id/eprint/2566

Actions (login required)

View Item
View Item