Gazali, Mohamad and Fatimah, Aden N. and Husni, Amir and Nurjanah, Nurjanah and Zuriat, Zuriat and Syafitri, Rina (2024) Antioxidant and Anti-Arthritic Activities of Green Seaweed Halimeda tuna Methanolic Extract. Squalen Bulletin of Marine and Fisheries Postharvest and Biotechnology, 19 (1). pp. 45-54. ISSN 20895690
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Abstract
Seaweed contains various bioactive compounds rich in pharmacological potentials, such as antioxidants and anti-arthritic. This study aims to determine the antioxidant and anti-arthritic activities of the methanolic extract of Halimeda tuna. Halimeda tuna samples were extracted using the maceration method and methanol. The methanol extract was tested for antioxidant (2,2-diphenyl-1-picrylhydrazyl (DPPH), ferric reducing antioxidant power (FRAP)) and anti-arthritic activity using denatured bovine serum albumin (BSA). The methanol extract was also subjected to phytochemical and Gas Chromatography-Mass Spectrometry (GC-MS) analysis. Research results revealed that the extract yield was 0.50 ± 0.06. Phytochemical analysis showed that H. tuna methanolic extract contained flavonoids, steroids, and alkaloids. GC-MS analysis showed that H. tuna methanolic extract contained steroids, fatty alcohols, and fatty acids. The antioxidant activity tests revealed an IC50 value of 299.98 ± 121.15 ppm and a FRAP value of 200.02 ± 8.50 n M/g, categorized as a weak antioxidant. Anti-arthritic activity of H. tuna methanolic extract showed an IC50 value of 877.29 ± 209.84 ppm. The anti-arthritic activity of H. tuna methanolic extract was lower than sodium diclofenac as a standard drug. The extract of H. tuna has antioxidant and anti-arthritic activities; hence, further exploration is needed as an alternative potential in the pharmacological field.
Item Type: | Article |
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Additional Information: | Cited by: 0; All Open Access, Gold Open Access |
Uncontrolled Keywords: | himelda tuna, phytochemical, DPPH, FRAP, GC-MS |
Subjects: | S Agriculture > S Agriculture (General) |
Divisions: | Faculty of Agriculture > Department of Fisheries |
Depositing User: | Laili Hidayah Hidayah |
Date Deposited: | 28 Aug 2024 07:13 |
Last Modified: | 28 Aug 2024 07:13 |
URI: | https://ir.lib.ugm.ac.id/id/eprint/3473 |