Maharini, Indri and Martien, Ronny and Nugroho, Akhmad Kharis and Supanji, Supanji and Adhyatmika, Adhyatmika (2021) Validation uv spectrophotometric method to determine entrapment efficiency of ocular polymeric nanoparticle levofloxacin hemihydrate. Research Journal of Pharmacy and Technology, 14 (10). 5479 – 5482. ISSN 09743618
Full text not available from this repository. (Request a copy)Abstract
Simple, easy, and economical UV spectrophotometric methods have been developed using simulated tear fluid (STF) solvent to determine levofloxacin hemihydrate (LEVH) levels in ocular nanoparticles, as indicated by the entrapment efficiency. A maximum wavelength of levofloxacin at 288nm, with a 4.0-12.0µg/mL concentration, shows linear results with a correlation coefficient (r) of 0.9997 and an average recovery of 99.920 –100.804. The developed method is able to use for the analysis of levofloxacin hemihydrate in nanoparticle preparations. © RJPT All right reserved.
| Item Type: | Article |
|---|---|
| Additional Information: | Cited by: 1 |
| Uncontrolled Keywords: | calcium chloride; levofloxacin; polymer nanoparticle; sodium chloride; solid lipid nanoparticle; accuracy; Article; controlled study; correlation coefficient; drug delivery system; drug formulation; drug release; drug solubility; lacrimal fluid; limit of detection; limit of quantitation; nerve compression; nonhuman; ultraviolet spectrophotometry; validation study |
| Subjects: | R Medicine > RS Pharmacy and materia medica |
| Divisions: | Faculty of Pharmacy |
| Depositing User: | Sri JUNANDI |
| Date Deposited: | 28 Sep 2024 05:29 |
| Last Modified: | 28 Sep 2024 05:29 |
| URI: | https://ir.lib.ugm.ac.id/id/eprint/4457 |
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