The role of aripiprazole in improvement of penile erection in schizophrenia patients with erectile dysfunction

Harahap, Debby Handayati and Marchira, Carla Raymondalexas and Solikhah, Eti Nurwening and Rizal, Dicky Moch (2021) The role of aripiprazole in improvement of penile erection in schizophrenia patients with erectile dysfunction. Medicinski Glasnik, 18 (2). 1683 – 1694. ISSN 18400132

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Abstract

Aim To provide evidence regarding the effectiveness of aripiprazole in improving penile erection with a therapeutic strategy of add-on or switching therapy in patients with schizophrenia. Methods. PubMed, Cochrane, Clinical Key, ProQuest, EBSCO-host, and ScienceDirect were searched for any design study that evaluated aripiprazole only or versus control (placebo or other antipsychotic) for erectile dysfunction in patients with schizophrenia. Three studies were identified and analysed from 295 initial articles. Data were then extracted from the studies and summarized descriptively. Results Two hundred ninety-five articles were screened, and three studies were identified and eventually selected. After the add-on or switching antipsychotic therapy to aripiprazole, the prevalence of erectile dysfunction and the score of erectile dysfunction or penile erection assessed by Nagoya and Sexual Function Questionnaire (NSFQ) and Arizona Sexual Experience Scale (ASEX) decreased. Conclusion Aripiprazole was effective to improve penile erectile function in patients with schizophrenia. The therapeutic strategy is adjunctive treatment or switching therapy to aripiprazole. © 2021, Medical Association of Zenica-Doboj Canton. All rights reserved.

Item Type: Article
Additional Information: Cited by: 0; All Open Access, Gold Open Access
Uncontrolled Keywords: aripiprazole; neuroleptic agent; Article; data extraction; drug efficacy; drug therapy; erectile dysfunction; follow up; galactorrhea; health care; human; meta analysis; penis erection; prevalence; questionnaire; schizophrenia; sexual function; systematic review
Subjects: R Medicine > RB Biomedical Sciences
Divisions: Faculty of Medicine, Public Health and Nursing > Biomedical Sciences
Depositing User: Sri JUNANDI
Date Deposited: 27 Sep 2024 05:52
Last Modified: 27 Sep 2024 05:52
URI: https://ir.lib.ugm.ac.id/id/eprint/4545

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