Permatasari, Lina and Riyanto, Sugeng and Rohman, Abdul (2021) Isolation and spectroscopic analysis of compounds from baccaurea racemosa (Reinw. ex blume) müll. arg. pulp. Tropical Journal of Natural Product Research, 5 (8). 1434 – 1438. ISSN 26160684
Full text not available from this repository. (Request a copy)Abstract
The pulp of Baccaurea racemosa (Reinw. ex Blume) Müll. Arg. is reported to have active compounds with medicinal importance, such as anti-inflammatory and antioxidant activities. However, there has been no report of any isolated compounds from B. racemosa pulp. The present study aims to isolate and characterize the compounds from B. racemosa pulp and their antioxidant activity. The powdered pulp of B. racemosa was extracted using methanol and was partitioned using n-hexane, dichloromethane and ethyl acetate to get corresponding fractions. The ethyl acetate fraction was isolated using conventional column chromatography to obtain compounds 1 and 2. Based on the spectrometric analyses (1D-NMR, 2D-NMR, infrared and GC-MS), compounds 1 and 2 were identified as 5-Hydroxymethylenefurfural (5-HMF) and tartaric acid, respectively. The compound 5-HMF showed antioxidant activity with IC50 > 7.94 mM. This study is the first report related to the isolation and identification of compounds from B. racemosa pulp, therefore 5-HMF from B. racemosa may be potentially used as a candidate for natural antioxidants. © 2021 Permatasari et al.
Item Type: | Article |
---|---|
Additional Information: | Cited by: 0; All Open Access, Hybrid Gold Open Access |
Uncontrolled Keywords: | 5 hydroxymethylfurfural; acetic acid ethyl ester; Baccaurea racemosa extract; butylcresol; dichloromethane; hexane; methanol; plant extract; tartaric acid; unclassified drug; antiinflammatory activity; antioxidant activity; Article; attenuated total reflectance Fourier transform infrared spectroscopy; Baccaurea racemosa; column chromatography; controlled study; DPPH radical scavenging assay; drug determination; drug identification; electron impact mass spectrometry; electrospray mass spectrometry; enzyme linked immunosorbent assay; fruit pulp; IC50; infrared spectroscopy; liquid liquid extraction; mass fragmentography; medicinal plant; nonhuman; nuclear magnetic resonance spectroscopy; phytochemistry; thin layer chromatography |
Subjects: | R Medicine > RS Pharmacy and materia medica |
Divisions: | Faculty of Pharmacy |
Depositing User: | Sri JUNANDI |
Date Deposited: | 26 Sep 2024 08:14 |
Last Modified: | 26 Sep 2024 08:14 |
URI: | https://ir.lib.ugm.ac.id/id/eprint/4621 |