Armenda, Syifa and Rusmawatiningtyas, Desy and Makrufardi, Firdian and Arguni, Eggi (2021) Factors associated with clinical outcomes of pediatric dengue shock syndrome admitted to pediatric intensive care unit: A retrospective cohort study. Annals of Medicine and Surgery, 66. ISSN 20490801
Full text not available from this repository. (Request a copy)Abstract
Background: Dengue shock syndrome (DSS) in children is a challenging infectious disease due to its high mortality rate. Several factors can contribute to the DSS patients’ outcomes. Here we defined factors associated with clinical outcomes of patients with DSS in Pediatric Intensive Care Unit (PICU). Methods: We retrospectively collected data from January 2016 to May 2020 of patients who had been diagnosed with DSS and admitted to PICU in our tertiary referral hospital. Bivariate analysis and logistic regression were used to evaluate independent predictors of the study outcomes. Results: Overall, 146 patients were enrolled in this study, including 53.4 males and 46.6 females. The mortality rate during the study period was 5.5. Fluid overload percentage, shock condition at PICU admission, DIC, and AKI were independent predictors for DSS mortality in logistic regression test with p < 0.05. There were several factors correlated with prolonged stay, including disseminated intravascular coagulation (DIC) (RR 15.26; 95 CI: 4.97–46.81), and nutritional status (RR 16.47; 95 CI: 3.72–72.9). Conclusion: Fluid overload percentage, shock condition at PICU admission, DIC, and AKI are independent predictors for DSS mortality. Several factors contribute to prolonged PICU stay, including DIC and nutritional status. © 2021
Item Type: | Article |
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Additional Information: | Cited by: 4; All Open Access, Gold Open Access, Green Open Access |
Uncontrolled Keywords: | Article; blood transfusion; body mass; body weight; child; clinical outcome; cohort analysis; data analysis; demography; dengue shock syndrome; disseminated intravascular clotting; diuresis; female; fluid resuscitation; follow up; human; information processing; intensive care unit; length of stay; male; mortality; mortality rate; nutritional status; outcome assessment; pediatric intensive care unit; preschool child; retrospective study; risk factor; systolic blood pressure; tertiary care center; urine volume |
Subjects: | R Medicine > RS Pharmacy and materia medica |
Divisions: | Faculty of Medicine, Public Health and Nursing > Biomedical Sciences |
Depositing User: | Sri JUNANDI |
Date Deposited: | 26 Sep 2024 00:49 |
Last Modified: | 26 Sep 2024 00:49 |
URI: | https://ir.lib.ugm.ac.id/id/eprint/4640 |