Giant placental chorangioma: The first case report in Indonesia

Theresia, Emilia and Siti Nurdiati, Detty and Widodo, Irianiwati (2021) Giant placental chorangioma: The first case report in Indonesia. Human Pathology: Case Reports, 23. ISSN 22143300

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Abstract

Giant placental chorangioma is a benign non-trophoblastic neoplasm which is rare but often results in serious prenatal complications and adverse pregnancy outcome. Here, we present the first case report of giant placental chorangioma in Indonesia with good clinical outcome, prenatally detected in a 35-year-old G4P2A1 female patient, who presented at 33 weeks of gestation with placenta previa, hemorrhage, anemia, and cardiomegaly. The color Doppler ultrasonography examination showed a large cystic hypoechoic circumscribed intraplacental mass in the parenchymal placenta. The elected caesarian section and mass removal was performed at 36 weeks of gestation. The microscopic appearance of the tumor showed a proliferation of capillary sized vessels with monomorphic endothelial cells. The tumor cells showed immunoreactivity for CD31, CD34, and smooth muscle actin (SMA). The Ki-67labeling index was 30. Clinical, radiological, histopathological, and immunohistochemical profiles confirmed the diagnosis of giant placental chorangioma. © 2021 The Author(s)

Item Type: Article
Additional Information: Cited by: 2; All Open Access, Gold Open Access
Uncontrolled Keywords: CD34 antigen; hemoglobin; Ki 67 antigen; platelet endothelial cell adhesion molecule 1; smooth muscle actin; adult; angioma; Apgar score; Article; cardiomegaly; case report; clinical article; computer assisted tomography; Doppler ultrasonography; female; histopathology; human; human tissue; immunohistochemistry; leukocyte count; placenta disorder; placental chorangioma; placental delivery; pneumonia
Subjects: R Medicine > RB Pathology
Divisions: Faculty of Medicine, Public Health and Nursing > Public Health and Nutrition
Depositing User: Sri JUNANDI
Date Deposited: 25 Sep 2024 00:31
Last Modified: 25 Sep 2024 00:31
URI: https://ir.lib.ugm.ac.id/id/eprint/4700

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