Murni, Indah K. and Prawirohartono, Endy P. and Triasih, Rina (2021) Potential Role of Vitamins and Zinc on Acute Respiratory Infections Including Covid-19. Global Pediatric Health, 8. ISSN 2333794X
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Abstract
Background. Vitamin C, E, D, A, zinc are considered to be essential in preventing and treating of acute respiratory infections (ARI) including COVID-19. Methods. We reviewed published studies evaluating the potential roles of these vitamin and zinc for ARIs and COVID-19 using Medline database, medRxiv, and bibliographic references. Results. Vitamins C, D, and E did not reduce incidence of common cold in general, but vitamin C reduced by half in population with physical and environment stresses. Vitamins C and E shortened duration and reduced severity of common cold. A large-dose vitamin A had no effect on recovery from pneumonia. Zinc improved clinical deterioration and pneumonia duration in under five. The effect on preventing COVID-19 morbidity and related-death was lacking. Conclusions. Although the effects of vitamins and zinc on ARIs including COVID-19 were inconclusive, taking these for a short period during pandemic may be beneficial when there is risks of deficiency. © The Author(s) 2021.
Item Type: | Article |
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Additional Information: | Cited by: 11; All Open Access, Gold Open Access, Green Open Access |
Uncontrolled Keywords: | antioxidant; ascorbic acid; calcitriol; cathelicidin; cyanocobalamin; interferon; interleukin 6; reactive oxygen metabolite; retinol; transferrin; vitamin; vitamin D; zinc; antiviral activity; artificial ventilation; B lymphocyte; cell differentiation; cell migration; coronavirus disease 2019; cytokine production; disease duration; dysphagia; hand disinfection; human; immune response; immunosuppressive treatment; incidence; inflammation; Influenza A virus; lymphocyte; morbidity; oxidative stress; oxygen saturation; patient care; physical activity; pneumonia; prevalence; publication; randomized controlled trial (topic); Review; Th1 cell; Th2 cell; vaccination; vitamin D deficiency; vitamin supplementation |
Subjects: | R Medicine > RB Biomedical Sciences |
Divisions: | Faculty of Medicine, Public Health and Nursing > Public Health and Nutrition |
Depositing User: | Sri JUNANDI |
Date Deposited: | 13 Sep 2024 04:19 |
Last Modified: | 13 Sep 2024 04:19 |
URI: | https://ir.lib.ugm.ac.id/id/eprint/4881 |