Dinarti, Lucia Kris and Anggrahini, Dyah Wulan and Lilyasari, Oktavia and Siswanto, Bambang Budi and Hartopo, Anggoro Budi (2021) Pulmonary arterial hypertension in Indonesia: Current status and local application of international guidelines. Global Heart, 16 (1). ISSN 22118160
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Abstract
Recent advances in the diagnosis and management of pulmonary arterial hypertension (PAH) have led to a significant improvement in the outcomes for patients with PAH. However, prompt and accurate diagnosis of PAH remains an unmet challenge due to lack of awareness and lack of meticulous data to profile the etiology and pathophysiology of this rare progressive disease, especially in low- and middle-income country. In Indonesia, the true prevalence and incidence of different subtypes of PAH in general population is still unknown. The Congenital HeARt Disease in adult and Pulmonary Hypertension (COHARD-PH) registry was the first single-center prospective registry in Indonesia, which indicated that almost 80 of adult patients with congenital heart disease (CHD) had experienced PAH and even Eisenmenger syndrome due to delayed diagnosis. Screening for early detection of asymptomatic CHD in children is yet to be systematically established in Indonesia, leading to undiagnosed and uncorrected CHD in adulthood. There are no specific national guidelines focusing on diagnostic workup and treatment of PAH in Indonesia. Furthermore, the lack of adequate diagnostic facilities, limited treatment availability, and limited drug coverage under the National Health Insurance Scheme are key issues that remain unaddressed. This review focuses on the diagnosis, treatment, and management of PAH associated with CHD in Indonesia as per international guidelines. We have proposed recommendations to effectively control and prevent PAH associated with CHD in Indonesia. The paper should be of interest to readers in the area of medical management and policy makers especially in low- and middle-income countries. © 2021 The Author(s).
Item Type: | Article |
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Additional Information: | Cited by: 7; All Open Access, Gold Open Access, Green Open Access |
Uncontrolled Keywords: | Adult; Eisenmenger Complex; Female; Heart Defects, Congenital; Humans; Hypertension, Pulmonary; Indonesia; Pregnancy; Pulmonary Arterial Hypertension; antihypertensive agent; vasodilator agent; clinical research; congenital heart disease; early diagnosis; health care policy; human; Indonesia; maternal mortality; practice guideline; priority journal; prognostic assessment; pulmonary hypertension; Review; risk assessment; adult; congenital heart malformation; Eisenmenger complex; female; pregnancy; pulmonary hypertension |
Subjects: | R Medicine > RB Biomedical Sciences |
Divisions: | Faculty of Medicine, Public Health and Nursing > Biomedical Sciences |
Depositing User: | Sri JUNANDI |
Date Deposited: | 12 Sep 2024 07:39 |
Last Modified: | 12 Sep 2024 07:39 |
URI: | https://ir.lib.ugm.ac.id/id/eprint/4926 |