Microencapsulation of Ethyl Acetate Extract from Green Coffee Beans (<i>Coffea Canephora</i>) by Spray Drying Method

Husni, Muhammad Ali and Nugroho, Akhmad Kharis and Fakhrudin, Nanang and Sulaiman, Teuku Nanda Saifullah (2021) Microencapsulation of Ethyl Acetate Extract from Green Coffee Beans (<i>Coffea Canephora</i>) by Spray Drying Method. INDONESIAN JOURNAL OF PHARMACY, 32 (2). pp. 221-231. ISSN 2338-9486

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Abstract

Coffee contains caffeine and chlorogenic acid (CGA) as the main constituents benefiting human health. Extract of green coffee beans (GCB) has some limitations in terms of its unpleasant flavour, aroma, and phytoconstituents bioactivity. This study aimed to encapsulate the crude ethyl acetate (EtOAc) extracts of Gayo Robusta GCB (Coffea canephora) to overcome its limitation. Microencapsulation was carried out by spray drying method using whey protein concentrate (WPC) as a coating material to produce nutraceutical supplement microparticles. The size of microparticles, morphology, and physicochemical characteristics were investigated. We found that the yield of microparticles was 39.5%, and the mean volume diameter was 1.367 mu m (span 1.162). The morphology of the microparticles was irregular microspheres with dense, wrinkled, shriveled, compact, and relatively homogeneous structural shape. The physicochemical properties measurement indicated that the microparticles had a radical scavenging activity value (RSA) of 374.53 mu g/mL, total phenol content (TPC) of 6.92 mg GAE/g, caffeine content of 9.12%, and CGA level of 7.19%. The spray drying microencapsulation using WPC was able to engulf and package the unpleasant flavour and aroma of the crude extract of Gayo Robusta GCB, producing an abundant yield, small and narrow range-sized particle, as well as protecting and carrying considerable amounts of phytoconstituents bioactivity.

Item Type: Article
Uncontrolled Keywords: spray drying microencapsulation; green coffee bean; chlorogenic acid; caffeine; whey protein concentrate
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Pharmacy
Depositing User: Sri JUNANDI
Date Deposited: 19 Oct 2024 06:10
Last Modified: 19 Oct 2024 06:10
URI: https://ir.lib.ugm.ac.id/id/eprint/9212

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